Clinical symptoms of biotin deficiency in animals

D Balnave - The American journal of clinical nutrition, 1977 - Am Soc Nutrition

...an im- portant role in intermediary metabolism (1). Biotinis so widely distributed in foods and
so abundantly produced by intestinal bacteria that it is doubtful whether a sponta- neous biotin
deficiency ever occurs in the adult animalunless a biotinantagonist is present in the diet. ...