The relation to the course of avian malaria of biotin and a fat-soluble material having the biological activities of biotin

W Trager- The Journal of experimental medicine, 1947 -

...In the studies with avian malaria it was found that the concentration of biotinin the blood of infected
animalsincreased during the Ixriod of parasite rise in number and deeaeased as the infection
subsided (1). More extensive experiments have now confirmed the fact that the